Scientific Program - Experimental Therapeutics

Friday, May 19
Sierra Ballroom D

Parallel Session - Experimental Therapeutics

Moderators: Per Kogner, Holger Lode, Vito Pistoia

1:00

197

Huebener

Xenogeneic Immunisation with a Human Tyrosine Hydroxylase DNA Vaccine Is Effective Against Neuroblastoma In Vivo

1:15

198

Salcedo

Immunologic and Therapeutic Synergy of IL-27 and IL-2: Enhancement of T Cell Sensitization, Tumor-Specific CTL Reactivity and Complete Regression of Disseminated Neuroblastoma Metastases in the Liver and Bone Marrow

1:30

199

Zeng

Anti-Neuroblastoma Effect by Fractalkine Gene Therapy Combined with Targeted IL-2 Is Mediated by an Autocrine NK Cell Activation Loop

1:45

200

Wu

Natural Killer Cells with Anti-GD2 Antibodies Are Cytotoxic for Multidrug Resistant Neuroblastoma Cells and Inhibit Tumor Growth in Metastatic Sites in NOD/SCID Mice

2:00

201

Kalous

Fenretinide + PPMP Prolonged Survival in Neuroblastoma Xenografts

2:15

202

Harned

Synergistic Cytotoxicity for Multi-Drug Resistant Neuroblastoma Cell Lines of the bcl-2 Family Inhibitor ABT-737 in Combination with Fenretinide, Alkylating Agents, or Topoisomerase Inhibitors

2:30

203

Pagnan

Bortezomib Causes Cell Growth Arrest, Apoptosis, and Anti-Angiogenesis in Human Neuroblastoma: Therapeutic Reflections

2:45

204

Puppo

Topotecan Downregulates Vascular Endothelial Growth Factor Production Induced by Hypoxia in Neuroblastoma: Inhibition of Hypoxia-Inducible Factor-1α

3:00

205

Peng

The Inhibitory Activity of Zoledronic Acid on Neuroblastoma Bone Metastasis Involves, in Addition to an Antiosteoclast Activity, an Inhibition of Ras, Akt and Erk 1/2 ­ Mediated Tumor Cell Survival

3:15

206

Norris

p53 Functions as a Multidrug Sensitivity Gene in Childhood Neuroblastoma

3:30

207

Lau

Cyclooxygenase Inhibition Enhances p53 Nuclear Localization and Sensitizes Neuroblastoma Cells to Chemotherapy-Induced Apoptosis

3:45

208

Ponthan

Celecoxib Prevents Neuroblastoma Tumour Development and Potentiates the Cytotoxic Effect of Cytotoxic Drugs In Vitro and In Vivo

4:00

Break

   


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