Scientific Program - Experimental Therapeutics

Friday, May 19
Sierra Ballroom C/D

Plenary Session - Experimental Therapeutics

Moderators: Nai-Kong Cheung, Michelle Haber, Tohru Sugimoto

8:45

185

Danks

Neural Progenitor Cell-Directed Enzyme Prodrug Therapy (NDEPT) as Effective Treatment in a Preclinical Model of Metastatic Neuroblastoma

9:00

186

Dickson

Tumor Targeted Interferon-Beta Delivery

9:15

187

Takenouchi

Oncolytic Viral Therapy for Neuroblastoma Cells by Sindbis Virus

9:30

188

Norris

Selective Sensitization of Murine Neuroblastoma Tumors to Chemotherapy by a Novel Class of Non-Toxic Small Molecule Inhibitors of MRP1

9:45

189

Hogarty

Disabling ODC1 Inhibits Neuroblastoma Growth and Extends Survival in TH-MYCN Mice

10:00

Break

   

10:15

190

Evans

The Trk-Selective Tyrosine Kinase Inhibitor CEP-701 Shows Biological Activity Alone and with Chemotherapy in Pre-Clinical Models of Neuroblastoma

10:30

191

Weber

Downregulation of Kaiso-Like-1 (KL1) by MYCN Contributes to Chemoresistance in Neuroblastoma Cell Lines and Is Correlated with an Aggressive Subtype in Primary Neuroblastoma

10:45

192

Weixler

Characterization of a Novel Human Anti-GD2 Anti-Idiotypic Antibody GK8 DNA Vaccine for Immunotherapy in Neuroblastoma

11:00

193

Modak

Targeting of Vascular Endothelial Growth Factor Enhances 131I-3F8-Mediated Radioimmunotherapy of Human Neuroblastoma

11:15

194

Yamashiro

Upregulation of PLGF and Activin Inhibitors Rescues Neuroblastoma Angiogenesis during VEGF Blockade

11:30

195

Marshall

Combination α-Interferon and Histone Deacetylase Inhibitor Therapy Is a Highly Effective Anti-Angiogenic Strategy in Neuroblastoma

11:45

196

Sveinbjornsson

5-Lipoxygenase and Leukotriene Receptors Are Expressed in Childhood Neuroblastoma and Inhibition of the Leukotriene Synthesis Pathway Suppresses Tumour Growth

12:00

Lunch

   


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